⏳ Hormone Replacement Therapy (HRT) and BHRT: Bioidentical Hormones in Anti-Ageing
How hormone therapy is considered in the context of longevity
Hormone replacement therapy (HRT) replenishes the decline of hormones with age. Bioidentical hormones (BHRT) are forms identical to natural ones. We break down how this is used in anti-ageing.
What is HRT
HRT is a medical practice of replenishing hormones that decline with age. It is best known for menopause in women (estrogen, progesterone), but also includes androgens in men.
- Replenishes hormone decline.
- Used in menopause.
- Includes estrogen, progesterone.
- Also considered in men.
Bioidentical hormones (BHRT)
BHRT are hormones structurally identical to natural ones (estradiol, progesterone, testosterone). They differ from synthetic analogues. BHRT is often used in individual protocols.
- Identical to natural hormones.
- Estradiol, progesterone, testosterone.
- Differ from synthetic.
- Used in protocols.
Key hormones
| Hormone | Role | Use |
|---|---|---|
| Estrogen | Menopause, bones | Women |
| Progesterone | Estrogen balance | Women |
| Testosterone | Muscle mass, energy | Men/women |
HRT and anti-ageing
In anti-ageing, hormones are considered a factor affecting muscle mass, bone density, energy and cognitive function. However, data on a "rejuvenating" effect are limited and require caution.
- Affects muscles and bones.
- Energy and cognition.
- Rejuvenation data limited.
- Requires caution.
Risks
- Estrogen: risk of thrombosis, some cancers.
- Testosterone: cardiovascular risks.
- Regular lab monitoring needed.
- Contraindications in some conditions.
When to see a doctor
- Pronounced menopause symptoms.
- Reduced energy and muscle mass.
- Only by lab results.
- Under an endocrinologist.
What is HRT?
Hormone replacement therapy, replenishing the decline of hormones with age.
What are bioidentical hormones?
Hormones structurally identical to natural ones (estradiol, progesterone, testosterone).
Does HRT rejuvenate?
Data on rejuvenation are limited; it is a medical intervention.
Are bioidentical hormones safe?
"Bioidentical" does not mean "safer" — medical supervision is needed.
Who needs HRT?
Mainly for menopause symptoms, on a doctor's advice.
Which hormones are used?
Estrogen, progesterone, testosterone.
What are the risks?
Thrombosis, hormone-dependent cancers, cardiovascular risks.
Are lab tests needed?
Yes, hormone levels are determined before and during therapy.
Can it be done without a doctor?
No, hormone therapy without a doctor is dangerous.
Who monitors it?
An endocrinologist after a full examination.