🔥 Inflammation and Coenzymes: Regulation of NF-kB and COX-2
Inflammation is not an "enemy" but a signal; it all depends on its level
Inflammation is often blamed, but it's an important protective reaction. Problems begin when it becomes chronic. At the center are the molecules NF-kB and COX-2. Let's look at them.
What is inflammation
Inflammation is a protective reaction to damage or infection. It's useful in the acute form, but harmful when it becomes chronic.
- Protective reaction.
- To damage.
- Acute — useful.
- Chronic — harmful.
NF-kB
NF-kB is a protein that "switches on" inflammation genes. Its excessive activity strengthens the chronic process.
- Inflammation "switch."
- Turns on genes.
- Excess harms.
- Chronic process.
COX-2
COX-2 is an enzyme involved in producing substances that increase inflammation and pain.
- Enzyme.
- Substance production.
- Increases inflammation.
- Involved in pain.
Coenzymes
Coenzymes (CoQ10 and others) help cells work and protect against oxidative stress linked to inflammation.
- Help cells.
- Protect from stress.
- Energy.
- Reduce load.
Support
| Agent | How it works |
|---|---|
| Omega-3 | Reduces inflammation |
| Curcumin | Affects NF-kB |
| CoQ10 | Antioxidant |
Practice
- Omega-3 from fish.
- Vegetables and fruit.
- Turmeric and ginger.
- Less sugar.
- Sleep and movement.
- Consult a doctor.
What is inflammation?
A protective reaction to damage or infection.
What is NF-kB?
A protein that "switches on" inflammation genes.
What is COX-2?
An enzyme that increases inflammation and pain.
How do coenzymes help?
Protect cells from oxidative stress.
What reduces inflammation?
Omega-3, curcumin, vegetables.
Does omega-3 help?
Yes, studied for reducing inflammation.
Does curcumin affect NF-kB?
Studied for such an effect.
What increases inflammation?
Sugar, stress, lack of sleep.
Is it dangerous?
Chronic — yes, linked to risks.
When is a doctor needed?
With chronic inflammatory diseases.