Longevity Science: Extending Healthspan
Autophagy and fasting: how the body "cleans itself". Let's look at the mechanism, benefits and how to trigger it. Brief and clear.
mTOR and AMPK are two "conductors" of cellular metabolism. One drives growth and synthesis, the other energy saving and cleanup. Let's explore how diet, fasting and supplements manage this balance.
Muscles and metabolism in 60+: how to keep strength against sarcopenia. Protein, HMB and creatine, exercise and food sources.
Hormesis: how moderate stress (sauna, cold, physical exercise) extends life. Mechanisms, data and practical approaches.
Spermidine: activating autophagy and extending healthy life. Mechanism, sources, research data and limits.
Telomeres and telomerase: what they are, how they relate to aging and whether supplements can lengthen chromosomes. Mechanisms, research, real possibilities and limits.
Metabolic syndrome: 5 signs, how to recognize and what to do. Let's look at the role of nutrition, movement and why it matters for the heart.
Inflammaging is chronic systemic inflammation in aging. Let's look at causes, mechanisms and correction protocols.
Resveratrol and pterostilbene: comparison, role in longevity and sirtuins. Bioavailability, sources, mechanisms and what matters.
Biological age markers: which tests reflect the rate of aging. Let's look at telomeres, epigenetic clocks and lab indicators.
Omega-3 fatty acids for heart health and healthy aging. Let's look at EPA/DHA, dosages and food sources.
Quercetin, fisetin and luteolin: natural senolytics against senescent cells. Mechanisms, sources, what research shows, how to take.
Sirtuins SIRT1-SIRT7: what they are, role in DNA repair, metabolism and longevity. How to activate via resveratrol, NAD+, fasting and lifestyle. What science shows.
The role of NAD+ in aging: why the NAD+ coenzyme declines with age and how to restore it. NMN, NR and niacin — NAD+ precursors, their mechanisms, doses and what science says.
Hormone replacement therapy (HRT) and bioidentical hormones (BHRT) are used in anti-ageing. We break down what it is, benefits, risks and when to see a doctor.
Growth factors (growth hormone/IGF-1) and metabolic health: the role of IGF-1 in aging, links to longevity and nutrition. Let's look at it in detail.
Alpha-ketoglutarate (AKG) is a key molecule of the Krebs cycle studied in the context of longevity and reducing biological age. We break down the mechanisms, forms and dosages.
Senescent (aging) cells and 'zombie cells': how senolytics cleanse the body. Mechanism, candidates (dasatinib, quercetin, fisetin), stages of research.
Theories of aging: why we age from a biological standpoint. Telomeres, free radicals, mitochondria, epigenetics, senescent cells — what is proven and what really helps slow aging.
The geroscience paradigm proposes treating ageing as the common root of age-related diseases. We break down how this approach changes prevention and what role nutraceuticals play.
Exploring the science of longevity. Molecular mechanisms of aging and evidence-based methods to extend healthspan.
Senolytics, NAD+ therapy, geroprotectors, intermittent fasting — only peer-reviewed data.